This membrane makes the roof and floor of the interpeduncular cistern ( Fig. The membrane described by Liliequist was later found to be the diencephalic leaf of LM ( Matsuno et al., 1988). Liliequist performed pneumoencephalography on cadavers and noticed that air hesitates to move from the interpeduncular cistern to the chiasmatic cistern by an upwardly convex membrane extended from the DS to the mammillary bodies ( Liliequist, 1956, 1959). The LM was first described by Key and Retzius (1875). Arnau Benet, in Handbook of Clinical Neurology, 2020 Liliequist's membrane Such a marker for the human neural biological clock may have applications in medicine and psychiatry.Īli Tayebi Meybodi. In visually and neurological ly intact humans, the melatonin rhythm may represent the output of a stable oscillator with a signal entrained to the light-dark cycle and relatively free from acute perturbation by stress or changes in other hormones.
However, when both are present, they appear linked in time with a phase separation of 4.4-9.3 h. In relation to the melatonin and cortisol rhythms, the presence of one does not require that of the other. Patients with lesions in the neural pathway, described as controlling the pineal melatonin rhythm in animals, had a suppressed plasma melatonin rhythm similar to the depressed cortisol rhythm seen in other patients with lesions of the pituitary-adrenal axis. The stresses of insulin hypoglycemia, pneumoencephalography, and exercise were not associated with a rise in human plasma melatonin, although cortisol or other hormonal markers of stress did increase.
Delea, in Biological Markers in Psychiatry and Neurology, 1982 ABSTRACT
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